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Last Updated on March 12, 2025 by Alaina
Thinking about trying FactorFive Skincare Products? I tested the Spa Collection and here’s what happened!
Skincare has always been important to me, but now that I’m in my early 50s, I’m paying even more attention to what actually works. There are so many products out there that promise to smooth, tighten, and hydrate, but not all of them deliver.

So when FactorFive reached out and offered to send me a sample of their FactorFive Spa Collection, I was really curious.
At $215, this curated set includes two of their popular stem cell-powered anti-aging products:
Silk Nourishing Cream – a high-end moisturizer packed with growth factors to smooth and hydrate skin
Growth Factor Post-Treatment Facial Masks (3-pack) – ultra-hydrating sheet masks designed for post-treatment recovery and deep hydration
After using these FactorFive Skincare products for the last several weeks, here’s what I think!
What is FactorFive and How Does Their Skincare Work?
FactorFive is all about humanizing skincare. They’re backed by years of research and focus on helping skin replenish what it loses as we age.
They use ethically derived human stem cell conditioned media. Basically, FactorFive scientists work with adult stem cells (ASCs), the cells that are most active in producing growth factors in the body. These growth factors are essential for skin repair, collagen production, and maintaining that youthful look.
As we age, our skin produces fewer growth factors, leading to wrinkles, sagging, dryness, and a loss of elasticity. FactorFive captures these powerful growth factors from stem cells and infuses them into their skincare products. The idea is that by putting these missing components back into your skin, you’re essentially helping your skin “listen” and restart the natural repair process.
Sounds pretty amazing, right? But let’s talk about what I actually thought after using the FactorFive skincare products found in the Spa Collection!

Nourishing Silk – The Anti-Aging Powerhouse
What It Is
This is FactorFive’s signature anti-aging moisturizer, designed to deeply hydrate and visibly improve the look of wrinkles, firmness, and skin texture. It’s packed with their human stem cell growth factors, plus other nourishing ingredients to keep skin looking plump, youthful, and radiant. You get one 1.8 oz bottle of Nourishing Silk with the Spa Collection
Price for Full Size: $189 for 1.8 oz
Included in Spa Collection: Full-size bottle
My Thoughts After Several Weeks
I’ll be honest, due to the cost of this product on its own ($189), I had high expectations. But right away, I noticed a few things that made me understand why this is a premium product.
First, the texture is perfect. It’s lightweight, non-greasy, and absorbs super quickly without leaving behind any shine or sticky residue. My skin just drinks it up, and it instantly feels softer, smoother, and more hydrated.
One thing that really stood out to me? Many moisturizers I’ve tried give me instant hydration, especially in the dry areas around my nose and T-zone, but after about an hour, my skin starts feeling tight and dry again. With this one, I haven’t experienced that at all. My skin stays comfortable, hydrated, and smooth all day, which is a huge plus for me.

After using it morning and night for over a month, I’ve definitely seen improvements:
- My skin feels incredibly smooth and soft
- Fine lines, especially around my eyes, look less noticeable
- My T-zone stays hydrated without getting oily
- My skin tone looks more even, with less redness
I also love that there’s no overpowering scent, just a light, clean smell that fades quickly. And even though the price is way up there, you don’t need much per use. I’ve been using it daily for about five weeks, and I still have plenty left, which definitely helps justify the cost.
Now, the big question – Would I buy it again?
If it were in my budget, absolutely. It’s one of the best moisturizers I’ve tried, and it really does what it claims. If price isn’t an issue, this is an amazing anti-aging moisturizer that delivers noticeable results.

FactorFive Growth Factor Facial Masks – Hydration Boost in a Sheet Mask
What It Is
The next product in their Spa Collection are the single-use FactorFive Growth Factor Facial Masks. These masks are infused with stem cell growth factors, hydrating ingredients, and soothing botanicals to help repair, replenish, and deeply moisturize the skin. They’re designed for post-treatment recovery but also work great for everyday hydration if your skin needs an extra boost. You get three masks with the Spa Collection.
Price: $22 per mask ($66 for a 3-pack)
Included in Spa Collection: 3 masks
My Thoughts After Using Them
Right away, I noticed how cooling and refreshing the mask felt on my skin, it’s especially nice if you store it in the fridge before using it. The mask is soaked in product, but it’s not overly drippy or slimy, which I appreciate.
I left it on for 15 minutes, and when I removed it, my skin felt softer, plumper, and well-hydrated. No sticky residue, no greasy feeling, just fresh, glowing skin.
After using three of these over a few weeks, here’s what I noticed:
- Immediate hydration boost, especially in my dry-prone T-zone
- My skin looked brighter and fresher after each use
- No irritation at all, which is great since my skin can be sensitive
Now, my one complaint, like most one-piece sheet masks, the fit wasn’t perfect. I had some extra fabric around my eyes that didn’t lay flat, which was a little annoying. I personally prefer two-piece masks because they fit better and stay in place more easily.
Would I buy them again? Yes, but again, not all the time. At $22 per mask, I’d love to use them weekly, but realistically, I’ll probably use them bi-weekly or monthly as a skin treat.

Final Thoughts – Are FactorFive Skincare Products Worth It?
Let’s be real, FactorFive is expensive. But unlike a lot of high-end skincare that promises the world but does nothing, these products actually work.
The Silk Nourishing Cream has left my skin smoother, more hydrated, and looking healthier overall. The Growth Factor Post-Treatment Facial Masks are hydrating and soothing, and I love how refreshed my skin feels after using them.
Would I love for them to be more affordable? Absolutely. But if you’re looking for high-quality, science-backed skincare that delivers real results, FactorFive’s Spa Collection is definitely worth considering.
Where to Buy FactorFive Skincare
FactorFive skincare products are available directly on their website: FactorFiveSkin.com
They also have a store locator on their site where you can find spas and clinics that carry their products.
Have you tried FactorFive Skincare? Let me know in the comments if you have a favorite product!